In this talk, I will first recall a few standard results on predator-prey systems with or without Allee effect on the prey. Then I will present a brake-driven gene drive reversal model (spatialized population genetics) and show the link with the first part. Thanks to this link, a co-extinction result will be rigorously established and a co-invasion result will be partially proved, partially illustrated numerically. This is an interdisciplinary joint work with Vincent Calvez and Florence Débarre.